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3D Tumour Intelligence

BC-001

Response AnalysisRESEARCH MODE

Breast Cancer Spheroid Response Study

AssetOGC-2401CancerBreast CancerSubtypeTNBC, HER2-Model3D Tumour SpheroidLead ScientistDr. S. Mokoena
Review DiscussionAsk OSIEL About This Study

Study Summary

Scientific context and protocol

ATM/Chk1 pathway modulation may increase replication stress sensitivity in TNBC spheroids.

Linked AssetOGC-2401
Cancer / SubtypeBreast Cancer · TNBC, HER2-
Model3D Tumour Spheroid
InvestigatorsDr. Sarah Mokoena · Dr. J. Patel
ProtocolOG-PROT-3D-021
Start Date2026-09-18
Current StageResponse Analysis
Data ModeRESEARCH

Key Result

Day 7 response · illustrative scientific data

DRUG B

Strong Response

Review and replicate confirmation pending.

Viability18%
Tumour size-71%
Confidence0.92

Treatment Overview

Control and two intervention groups

Control0 · 3 replicates
Drug A0.1 µM · 3 replicates
Drug B0.8 µM · 3 replicates

Timepoints

Longitudinal image and response capture

Day 0Day 3Day 7

Current analytical timepoint: Day 7.

Study Timeline

Completed, current, and upcoming workflow

Setup
Samples
Treatment
Imaging
Segmentation & QC
Response Analysis
Scientific Review
Approved Result

Current Alerts

Research review required

Response Analysis review pendingNeeds Review
Passed QC status requires confirmationNeeds Review

Study Context

Current scientific record

StageResponse Analysis
QCPassed
ProtocolOG-PROT-3D-021
Images126
Last Updated2026-10-03

Current Attention

Research review queue

Response Analysis review pendingPassed QC status requires confirmation
Research data · human review required.