Loading study workspace…

GBM-004

ImagingRESEARCH MODE

Glioblastoma Penetration Study

AssetOGC-NS-321CancerGlioblastomaSubtypeIDH-wildtypeModelPatient-derived OrganoidLead ScientistDr. M. Rossi

Review Discussion Ask OSIEL About This Study

NEURAL 3D RECONSTRUCTION ENGINE

AI MRI-to-3D Model Converter & Tumour Highlighter

Connect raw 2D MRI slices to backend volumetric AI models to reconstruct true 3D organ geometry with sub-voxel tumour highlighter masking.

Initializing 3D Tumour Engine...

Three.js 3D Model • OSIEL-Biomed3D v2.8 (Volumetric UNet + Isosurface Converter)Left-drag to rotate • Right-drag to pan • Scroll to zoom

Zoom Scale110%Mask Opacity65%Organ Shell Opacity30%

Scan & Model Information

TimepointTreatment

Source File: T1-Gd_Axial_Brain_Lesion.dcm
File Size: 2.34 MB
Backend AI Model: OSIEL-Biomed3D v2.8 (Volumetric UNet + Isosurface Converter)
Confidence Score: 98.1%

Volumetric Segment

Globular

Tumour Volume36.25 cm³

Max 3D Diam44.6 mm

RAS Centroid(0.7, -13.2, 0.6) mm

Sphericity0.85

Tissue Sub-Compartments:

Necrotic (29%) Enhancing (49%) Edema

Hyper-intense lesion segmented at spatial coordinates (X: +0.7mm, Y: -13.2mm, Z: +0.6mm).
Total volumetric mass measured at 36.25 cm³ (36,251 mm³) with maximum 3D Feret diameter of 44.6 mm.
Multi-parametric decomposition indicates prominent active enhancing rim (49%) encasing a central necrotic core (29%).
Peritumoral hyper-intensity suggests moderate vasogenic edema extending ~6.9 mm into adjacent parenchyma.
Deep learning segmentation model (OSIEL-Biomed3D) reached 98% detection confidence with a Dice similarity coefficient of 0.951.

Compare treatment response

Imaging Sessions

Acquisition history · select a session

Study	Sample	Treatment	Timepoint	Modality	Instrument	Images	QC	Operator
GBM-004	GBM-004-R2	Drug B	Day 7	Brightfield	Research microscope	36	Passed	Imaging Core
GBM-004	GBM-004-R1	Control	Day 7	Fluorescence	Research microscope	28	Needs Review	Dr. J. Patel
GBM-004	GBM-004-R3	Drug A	Day 3	Z-stack	Research microscope	48	Passed	Imaging Core
GBM-004	GBM-004-R2	Drug B	Day 0	Brightfield	Research microscope	14	Passed	Imaging Core

Scientific Imaging Viewer

Illustrative acquisition preview · no real processing

Illustrative tumour microscopy image; not diagnostic or measurement-grade

ILLUSTRATIVE IMAGEScale: recorded metadata

Z-stack plane 6 / 12

Image Metadata

IMG-GBM004-017

ModalityBrightfield

TimepointDay 7

TreatmentDrug B

ReplicateR2

ScaleRecorded metadata

InstrumentResearch microscope

QCPassed

Image Count36