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PA-002

ApprovedRESEARCH MODE

PDAC Stromal Response Study

AssetOGC-PA-084CancerPancreatic CancerSubtypePDACModelCo-culture SpheroidLead ScientistDr. S. Mokoena

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NEURAL 3D RECONSTRUCTION ENGINE

AI MRI-to-3D Model Converter & Tumour Highlighter

Connect raw 2D MRI slices to backend volumetric AI models to reconstruct true 3D organ geometry with sub-voxel tumour highlighter masking.

Initializing 3D Tumour Engine...

Three.js 3D Model • OSIEL-Biomed3D v2.8 (Volumetric UNet + Isosurface Converter)Left-drag to rotate • Right-drag to pan • Scroll to zoom

Zoom Scale110%Mask Opacity65%Organ Shell Opacity30%

Scan & Model Information

TimepointTreatment

Source File: T1-Gd_Axial_Brain_Lesion.dcm
File Size: 2.34 MB
Backend AI Model: OSIEL-Biomed3D v2.8 (Volumetric UNet + Isosurface Converter)
Confidence Score: 97.0%

Volumetric Segment

Lobulated

Tumour Volume37.82 cm³

Max 3D Diam46.2 mm

RAS Centroid(7, 1.2, -3.6) mm

Sphericity0.74

Tissue Sub-Compartments:

Necrotic (38%) Enhancing (42%) Edema

Hyper-intense lesion segmented at spatial coordinates (X: +7mm, Y: +1.2mm, Z: -3.6mm).
Total volumetric mass measured at 37.82 cm³ (37,817 mm³) with maximum 3D Feret diameter of 46.2 mm.
Multi-parametric decomposition indicates prominent active enhancing rim (42%) encasing a central necrotic core (38%).
Peritumoral hyper-intensity suggests moderate vasogenic edema extending ~7.3 mm into adjacent parenchyma.
Deep learning segmentation model (OSIEL-Biomed3D) reached 97% detection confidence with a Dice similarity coefficient of 0.96.

Compare treatment response

Imaging Sessions

Acquisition history · select a session

Study	Sample	Treatment	Timepoint	Modality	Instrument	Images	QC	Operator
PA-002	PA-002-R2	Drug B	Day 7	Brightfield	Research microscope	36	Passed	Imaging Core
PA-002	PA-002-R1	Control	Day 7	Fluorescence	Research microscope	28	Needs Review	Dr. J. Patel
PA-002	PA-002-R3	Drug A	Day 3	Z-stack	Research microscope	48	Passed	Imaging Core
PA-002	PA-002-R2	Drug B	Day 0	Brightfield	Research microscope	14	Passed	Imaging Core

Scientific Imaging Viewer

Illustrative acquisition preview · no real processing

Illustrative tumour microscopy image; not diagnostic or measurement-grade

ILLUSTRATIVE IMAGEScale: recorded metadata

Z-stack plane 6 / 12

Image Metadata

IMG-PA002-017

ModalityBrightfield

TimepointDay 7

TreatmentDrug B

ReplicateR2

ScaleRecorded metadata

InstrumentResearch microscope

QCPassed

Image Count36